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Radiesse® is a dermal filler that is made of calcium-based microspheres suspended in a water-based gel. It is a great choice for facial contouring and for correcting facial asymmetries. Like the hyaluronic acid fillers (Restylane® and Juvederm®), it can help soften the lines of the nasolabial folds and marionette lines.

One of the many benefits of Radiesse® is that it delivers immediate results for patients looking to erase wrinkles and re-contour certain areas of their face. It can also improve symmetry, which has been shown to improve attractiveness. In addition to replenishing lost volume, Radiesse® also stimulates collagen production to promote a more long-term improvement. In many patients, this extended correction can last for up to one year.

Like the hyaluronic acid fillers, there are very few side effects. There is virtually no risk of allergic reaction, and the most common side effects are mild swelling and bruising.

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How Does it Work?

Radiesse®, formerly called Radiance, is a synthetic dermal filler made of calcium hydroxyapatite.



Radiesse®, formerly called Radiance, is a synthetic dermal filler made of calcium hydroxyapatite. It is used for soft tissue augmentation and to treat skin folds and wrinkles. Calcium hydroxyapatite is an inorganic substance similar to bone. No animals or animal products are used during its production, and no skin testing is needed.

When injected into the deep dermis and subcutis, Radiesse® provides a matrix into which the body’s own tissue can grow and add volume. In this way, it is used for soft tissue augmentation, and can help to fill in deep skin folds and wrinkles.

Radiesse Pricing

The extent of the procedure may involve one or several areas of the face, and the appropriate dosage for each area may vary, making it difficult to provide a meaningful cost estimate until you are examined by a doctor.

The average cost for Radiesse® is $600 per vial. 2-5 vials per average treatment.

What to Expect

The Radiesse® procedure is performed in the doctor’s office.

Here's what to expect:

The procedure is performed using BLT (Numbing Cream) with the assistance of microcannulas – a technique used to better distribute the product and alleviate post-injection bruising. Depending on the extent of the treatment, the procedure requires a short period for the numbing cream to take effect, as well as the time to perform the injection. This usually can be done in less than an hour.

Patients return home within minutes after the procedure!
The procedure involves injecting a compound of calcium hydroxyl apatite microspheres that are suspended in a carboxymethylcellulose gel. Calcium and phosphate ions, naturally occurring in our bodies, primarily make up the calcium hydroxyl apatite particles.

Results are fully evident within one week.
Radiesse® can last two years or more, but “touch ups” may be necessary throughout this time period.


What is RADIESSE® made from?

RADIESSE® is made of tiny calcium-based microspheres suspended in a water-based gel. The calcium microspheres are similar to minerals found naturally in the body so allergy testing is not required. Over time, the body absorbs the microspheres and gel, leaving behind only natural collagen.

Please note that RADIESSE® is contraindicated in patients with severe allergies manifested by a history of anaphylaxis, with a history or presence of multiple severe allergies (please see Important Safety Information below).

How does RADIESSE® work?
Once injected, RADIESSE® plumps the skin to give the appearance of a smoother surface. Over time, RADIESSE® works to stimulate the body to produce collagen naturally. Ultimately the body absorbs the product and leaves behind the natural collagen for long-lasting results.
Where can RADIESSE® be injected?

RADIESSE® can be injected in the following locations*:

– Smile lines: also called the nasolabial folds, are the lines that run from the corners of the nose to the corners of the mouth
– Marionette lines: the lines that run downward from the corners of the mouth
– Corners of the mouth: also called the oral commissure, if these are turned downward it can make you look as though you’re frowning
– Pre-jowl fold: the area on either side of the chin, where skin can sag due to loss of facial volume
– Chin wrinkles: horizontal lines that can form on your chin and distract from your smile
*RADIESSE® is FDA-approved for correction of moderate to severe facial wrinkles and folds, such as nasolabial folds.

How is treatment with RADIESSE® performed? Is it painful?
RADIESSE® is injected under the skin in a quick procedure that can be done over the lunch hour. RADIESSE® is also FDA-approved to mix with lidocaine (an anesthetic), which means the procedure will be much more comfortable. In fact, in a clinical study, 90% of patients treated reported significant pain reduction when injected with RADIESSE® mixed with lidocaine.
Who should not use RADIESSE®?
RADIESSE® should not be used in people who have an allergy to any component of the product. You should not use RADIESSE® if you are pregnant or breast feeding or if you are under 18 years of age.
What should I tell my doctor before taking RADIESSE®?
Tell your health care provider if you are taking blood thinners or medicines that can interfere with the clotting of blood, such as aspirin or warfarin. These medicines might make it more likely that you will experience bruising or bleeding at the injection site.
What are the most common adverse events with RADIESSE®?
The most common adverse events include bruising, redness, swelling, pain, tenderness and itching. These side effects generally last for a short time and are mild in nature. These are not all of the possible side effects with RADIESSE®. Tell your health care provider about any side effects that bother you or do not go away.
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* Medical Disclaimer

The medical information on this site is provided as an information resource only. It is not designed to and does not provide medical advice, professional diagnosis, opinion, treatment or services to you or to any other individual and is not to be used or relied upon for any diagnostic or treatment purposes. This information is not intended to be patient education, does not create any patient-physician relationship, and should not be used as a substitute for professional diagnosis and treatment. More information


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2019 © Facial Rejuvenation FL 3715 7th Terrace Vero Beach, FL 32960
Ph (772) 978-0484
Gerald Pierone Jr., M.D.


Gerald Pierone Jr., M.D.
3715 7th Terrace
Vero Beach, FL 32960
Gerald Pierone Jr., M.D.


Gerald Pierone Jr., M.D.
3715 7th Terrace
Vero Beach, FL 32960


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2020 © Facial Rejuvenation FL 3715 7th Terrace Vero Beach, FL 32960
Ph (772) 978-0484

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