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I am looking at many Plastic surgeon and Dermatologist websites. I noticed that many of them do not offer Bellafil. Is there a reason why? Bellafil was suggested to me and I am starting to wonder if Bellafil is good idea. Thank you in advance for your response.


5 star rating


Hello and thanks for posting.

I think that the main reason that many providers do not offer Bellafill is because of the risk of late granuloma formation.
Granulomas are delayed development of nodules in the areas of injection. When Bellafill was approved, the FDA mandated a 5 year post-marketing safety study to determine the risk of late complications. This study was completed and showed that there was a 1.7% risk of granuloma formation over 5 years (17 of 1000 patients developed granulomas in this study).

In my experience, granulomas are not fun, but represents a manageable problem. This involves a series of injections of triamcinolone and 5FU and this treatment reliably shrinks the nodules down.

There are also data from Europe and China suggesting that deep injection of PMMA onto bone further lessens the risk of granuloma because of the paucity of immunologic cells in this anatomic location.

In my opinion, as long as one is willing to accept this level of risk of granulomas, Bellafill is a great treatment option for long-term facial volume restoration.

I hope that this information helps and best of luck to you!

Dr. Pierone

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